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SMaHT Experimental and Computational Technology Development

Official title: Somatic Mosaicism across Human Tissues (SMaHT) Program: Experimental and Computational Technology Development (RM1 Clinical Trial Not Allowed)

Offered by Department of Health and Human Services

Award

Award varies

Estimated Application Due Date

Not specified

Eligible Area

National

Opens

May 1, 2027

Overview

Funds experimental and computational technology development for studying somatic mutations in human tissues. Fits research on biological processes and disease mechanisms linked to these mutations.

  • Focus: Somatic Mosaicism across Human Tissues (SMaHT) Network
  • Purpose: Advance discovery of processes and disease mechanisms tied to somatic mutations
  • Foundation: Multi-omic mutation datasets from tissues spanning all three germ layers
  • Clinical trials: Not allowed

Who Can Apply

  • Eligible: Indian/Native American tribal governments other than federally recognized tribes
  • Eligible: Eligible agencies of the federal government
  • Eligible: U.S. territories or possessions
  • Eligible: Faith-based or community-based organizations
  • Eligible: Regional organizations
  • Eligible: Non-U.S. entities (foreign institutions)

Grant Details

Award Amount

Award varies

Eligible Area

National · Nationwide (federal)

Opens

May 1, 2027

Estimated Application Due Date

Not specified

Contact & Funder Details

Websitehhs.gov
Nonprofit Status501(c)(3) status not required

How To Apply

Apply directly on Department of Health and Human Services's website. Confirm current details before applying.

Go to the application

This page was last reviewed October 1, 2026 and last updated October 1, 2026.

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